Why is midazolam given in the buccal space?

The midazolam solution should be placed against the sides of the gums and cheek so that the medicine is absorbed directly into the bloodstream. This is known as the buccal or oromucosal route. If the medicine is swallowed accidentally, it might not work as quickly.

How do you administer buccal midazolam Epistatus 10mg in 1ml?

Slowly administer approximately half of the solution to the buccal cavity on one side of the mouth, and then administer the remainder slowly to the other side, by pressing the syringe plunger until it stops.

Who can give buccal midazolam?

Buccolam® can be used by parents and carers to treat seizures in children under 18 years of age. Epistatus® can be used to treat seizures in children aged 10 to 17. The medicines are not licensed for treatment of adults; however, a doctor may prescribe it for an adult if they feel it is suitable.

Is Epistatus a controlled drug?

Midazolam is a schedule 3 controlled drug. This means there are some specific requirements when writing a prescription for Epistatus: Include the patient’s title, forename, surname, address and age. State the name and form of the drug, strength of the preparation, and dose to be taken.

Why is midazolam used for epilepsy?

Drugs, such as midazolam, are used to abort ongoing seizures and thereby avoid the complications of prolonged status epilepticus. The drugs resolve the majority of emergency presentations and they work best if given soon after the seizure has exceeded five minutes.

When do we give buccal midazolam?

Buccal Midazolam may be given when a child or young person with epilepsy has: • a generalised convulsive seizure lasting more than 5 minutes. (These are seizures where the child does not respond, continues to be stiff and may jerk their arms and legs).

How is midazolam given?

Midazolam can also be administered in combination with anticholinergics. For this indication midazolam should be administered IV or IM, deep into a large muscle mass 20 to 60 minutes before induction of anaesthesia), or preferably via the rectal route in children (see below).

Does midazolam make you sleep?

Midazolam injection is used to produce sleepiness or drowsiness and relieve anxiety before surgery or certain procedures.

What is midazolam used for in medical emergency?

About buccal midazolam Buccal midazolam is an emergency rescue medication used to stop a seizure if one occurs in a child with epilepsy. This leaflet is for parents or carers who may need to give rescue medication to a child with epilepsy who is having a seizure.

What are the side effects of midazolam?

Midazolam injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache.
  • drowsiness.
  • nausea.
  • vomiting.
  • hiccups.
  • coughing.
  • pain, redness, or hardening of the skin at the injection site.

What is Epistatus used for?

Epistatus 10 mg oromucosal solution contains the medicine midazolam, which belongs to a group of medicines known as benzodiazepines. Epistatus is used to stop a prolonged, convulsive seizure (‘fit’) in children and adolescents aged 10 to less than 18 years.

Is midazolam used for seizures?

Midazolam (meh-daz-owe-lam) is a medication that is commonly used as emergency treatment for seizures. It is a benzodiazepine (ben-zo-die-az-eh-peen) medication like diazepam (valium) or clonazepam (clonn-az-eh-pam). Midazolam works more quickly than diazepam but does not last as long.

How fast does midazolam work?

The onset of action is about 2 minutes after the injection. Maximum effect is obtained in about 5 to 10 minutes. The IV injection of midazolam should be given slowly at a rate of approximately 1mg in 30 seconds.

What is midazolam injection used for?

Can midazolam stop breathing?

IMPORTANT WARNING: has been expanded. Midazolam injection may cause serious or life-threatening breathing problems such as shallow, slowed, or temporarily stopped breathing that may lead to permanent brain injury or death.