## What is the MDRD formula?

Notes: The original Modification of Diet in Renal Disease (MDRD) equation was based on 6 variables: age, sex, ethnicity, serum creatinine, urea, and albumin (often referred to as MDRD 6). Subsequently, the MDR was simplified to a 4-variable version (MDRD-4) that included age, sex, ethnicity, and serum creatinine.

**What is MDRD study?**

The Modification of Diet in Renal Disease (MDRD) study consisted of two randomized clinical trials that investigated whether protein restriction and control of blood pressure had an effect on the progression of chronic kidney disease (CKD).

**When is MDRD used?**

The Modification of Diet in Renal Disease (MDRD) Study equation and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation are the most widely used IDMS traceable equations for estimating GFR in patients age 18 and over.

### When do you use MDRD vs CKD?

As expected, CKD-EPI estimated GFR closest to the directly measured GFR in patients with a GFR of ≥90 ml/min per 1.73 m2, whereas MDRD remained best when GFR ranged from 15 to 29 ml/min per 1.73 m2.

**How is creatinine clearance calculated?**

Creatinine Clearance Calculator Creatinine Clearance = [[140 – age(yr)]*weight(kg)]/[72*serum Cr(mg/dL)] (multiply by 0.85 for women). The results you receive from this tool are for informational purposes only and should not be the basis of your medical decision making.

**What does GFR 90 mL/min 1.73m2 mean?**

An eGFR of >90 ml/min/1.73m2 is considered normal kidney function. If these patients have evidence of kidney disease* (see below) these patients have CKD stage G1. Patients with an eGFR of 60-90 ml/min/1.73m2 have mildly reduced kidney function which may be appropriate for their age.

#### What does 1.73 m2 mean in GFR?

The average eGFR for someone in their 20s is about 116 mL/min/1.73m2. It drops to 85 mL/min/1.73m2 for people in their 60s. An eGFR higher than 60 means you have at least 60% kidney function. Generally, the higher the number, the better your kidney function.

**What is the MDRD equation?**

MDRD Study Equation. eGFR =. 175 x (S Cr) -1.154 x. (age) -0.203 x. 0.742 [if female] x. 1.212 [if Black]

**What is MDRD formula?**

Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values.

## What is a normal MDRD GFR?

What is a normal MDRD GFR? “Normal” GFR is usually >90 ml/min/1.73m2. (Note the correction for body surface area “per 1.73m2” which is important for certain patient groups, e.g. amputees, extremes of body habitus.) It is best to follow the locally calculated eGFR if possible although one can be calculated using an eGFR calculator.

**What is MDRD stand for?**

MDRD: Modification of Diet in Renal Disease: MDRD: Mobilization, Deployment, Redeployment and