What is the brand name for efavirenz emtricitabine tenofovir?
ATRIPLA is a fixed-dose combination tablet containing efavirenz, emtricitabine, and tenofovir DF. SUSTIVA is the brand name for efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI).
What are tle tablets?
The current first-line regimen for HIV treatment in many countries is the combination of TDF, 3TC, and EFV; that is, two NRTIs and one NNRTI. This regimen is generally referred to as TLE because it has T (TDF), L (lamivudine, also known as 3TC) and E (efavirenz).
What is efavirenz used for?
Efavirenz is used in combination with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Why is efavirenz taken at night?
Efavirenz is dosed once daily, and is generally administered in the evening owing to its central nervous system side-effects.
Can the dose of efavirenz and emtricitabine and tenofovir be adjusted?
Because efavirenz, emtricitabine and tenofovir disoproxil fumarate is a fixed-dose combination tablet, the dose of efavirenz, emtricitabine and tenofovir disoproxil fumarate cannot be adjusted for patients of lower weight [see Warnings and Precautions (5.2, 5.9 ), Adverse Reactions (6.1), and Clinical Pharmacology (12.3)].
What happens when you stop taking efavirenz and lamivudine?
If you have HBV and you take efavirenz, lamivudine and tenofovir, your condition may suddenly worsen when you stop taking efavirenz, lamivudine and tenofovir. Your doctor will examine you and order lab tests regularly for several months after you stop taking efavirenz, lamivudine and tenofovir to see if your HBV has worsened.
How many milligrams of efavirenz are in a tablet?
Each tablet contains 600 mg of efavirenz, 200 mg of emtricitabine, and 300 mg of tenofovir disoproxil fumarate (equivalent to 245 mg of tenofovir disoproxil).
What is the recommended dose of didanosine with efavirenz and disoproxil?
In patients weighing greater than 60 kg, reduce the didanosine dose to 250 mg when it is coadministered with efavirenz, emtricitabine and tenofovir disoproxil fumarate. In patients weighing less than 60 kg, reduce the didanosine dose to 200 mg when it is coadministered with efavirenz, emtricitabine and tenofovir disoproxil fumarate tablets.