Can statins cause bladder problems?
Statin use is associated with an increased risk of bladder pain syndrome/interstitial cystitis (BPS/IC), according to investigators in Taiwan.
Do statins cause urinary retention?
Conclusion: The findings of this case support the potential risk of permanent bladder smooth muscle damage due to statin that may lead to underactive bladder and urinary retention.
What are the symptoms of an underactive bladder?
Symptoms of an underactive bladder include:
- Needing to wait for the flow to start or hesitancy.
- Needing to push and strain to empty the bladder.
- Poor or slow urinary stream.
- Stop and start urinary stream.
- Prolonged time required to pass urine.
- Feeling like the bladder has not emptied completely.
How do you manage an underactive bladder?
Self-catheterization: This is the mainstay of effective treatment for underactive bladder. Self-catheterization involves learning to pass a disposable catheter into the urinary bladder at least four times daily in order to empty it completely.
What is bladder urothelium?
The urothelium is a highly specialized type of tissue that lines the inside of your urinary tract. It serves as a barrier, preventing urine (pee) from leaking out into your body. It also stretches and contracts as your bladder fills and empties.
Can statins cause urinary incontinence?
Abstract. Introduction: Statin may induce epithelial dysfunction of the bladder urothelium. Epithelial dysfunction was proposed as one of the major potential etiologies for bladder pain syndrome/interstitial cystitis (BPS/IC).
Is underactive bladder serious?
Underactive Bladder Syndrome is a chronic, complex and debilitating disease which affects the urinary bladder with serious consequences.
How do they test for underactive bladder?
Underactive bladder (UAB) is a common and poorly understood condition, with limited treatment options. It is frequently misdiagnosed as overactive bladder (OAB) and bladder outlet obstruction (BOO). It can only be reliably diagnosed with invasive pressure flow studies (PFS).
Can you fix an underactive bladder?
There are a number of treatments available to address the various conditions associated with underactive bladder and include techniques to promote and assist bladder emptying. None of these is a cure – they are designed to treat symptoms of the disease.
What is Uroepithelium?
the uroepithelium is an epithelial tissue that lines the distal portion of the urinary tract, including the renal pelvis, ureters, bladder, upper urethra, and glandular ducts of the prostate.
What medications cause urinary incontinence?
Pharmacologic agents including oral estrogens, alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, nonsteroidal anti-inflammatory drugs, and calcium channel blockers have been implicated to some degree in the onset or exacerbation of urinary incontinence.
What does urinary reflux feel like?
burning sensation when passing urine. wanting to urinate more often, if only to pass a few drops. cloudy, bloody or very smelly urine. pain in the lower part of the body.
When should you suspect vesicoureteral reflux?
A VCUG is usually done if: a child has had one UTI with fever and a kidney ultrasound shows a problem. an infant or young child under 2 years who has had 2 or more UTIs with fever.
What is the bladder urothelium?
What is Uroplakin?
Uroplakins are cell membrane proteins, which form urothelial plaques on the surface of each urothelial cell. Four types of uroplakins are known in humans – UPIa, UPIb, UPII, UPIII.
Why won’t my bladder empty completely?
When the bladder is full, you urinate and the waste leaves your body. However, if you have urinary retention, your bladder doesn’t completely empty when you urinate. This can happen to both men and women and it can be caused by things like blockages, medications or nerve issues.
How can I stimulate my bladder to pee?
If you do have to force yourself, here are 10 strategies that may work:
- Run the water. Turn on the faucet in your sink.
- Rinse your perineum.
- Hold your hands in warm or cold water.
- Go for a walk.
- Sniff peppermint oil.
- Bend forward.
- Try the Valsalva maneuver.
- Try the subrapubic tap.
What causes urine to back up in bladder?
A blockage where the ureter and bladder meet (ureterovesical junction) may cause urine to back up into the kidneys. Ureterocele. If a ureter is too narrow and doesn’t allow urine to flow completely, a tiny bulge in the ureter (ureterocele) may develop.
What are the symptoms of statin side effects?
There are different symptoms you may experience. The most common is muscle pains or cramps, also called myalgias. You may experience muscle inflammation and an elevated marker of muscle injury called creatine kinase. You may experience these symptoms or similar ones while taking statins.
The primary symptom of an underactive bladder is withholding large amounts of urine without the sensation to release it. Even when a patient with an underactive bladder attempts to release it, they do not have the sensation of an empty bladder and often force urine out.
How can I relieve statin side effects?
To relieve statin side effects, your doctor may recommend several options. Discuss these steps with your doctor before trying them: Take a brief break from statin therapy. Sometimes it’s hard to tell whether the muscle aches or other problems you’re having are statin side effects or just part of the aging process.
Do statins cause muscle pain?
The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult. Oddly enough, most randomized controlled studies of statins indicate that people taking statins develop muscle pain at the same rate as people taking placebo.